منابع مشابه
Regulatory RNAs in Bacteria
Bacteria possess numerous and diverse means of gene regulation using RNA molecules, including mRNA leaders that affect expression in cis, small RNAs that bind to proteins or base pair with target RNAs, and CRISPR RNAs that inhibit the uptake of foreign DNA. Although examples of RNA regulators have been known for decades in bacteria, we are only now coming to a full appreciation of their importa...
متن کاملNoncoding regulatory RNAs database
The noncoding RNAs database is a collection of currently available sequence data on RNAs, which have no protein-coding capacity and have been implicated in regulation of cellular processes. The RNAs included in the database form very heterogenous group of molecules that act on different levels of information transmission in the cell. It includes RNAs acting on the level of chromatin structure, ...
متن کاملRegulatory RNAs and beyond
numerous noncoding rnas (ncrnas) have been dis covered in prokaryotes. Most do not exceed 200 nucleotides in length and have thus been termed small rnas (srnas). Many act by an antisense mechanism and bind to their target—primarily messenger rnas (mrnas)—through short stretches of Watson–crick (Wc) base pairs, often interspersed with non-Wc base pairs or mismatches, which makes reliable pre dic...
متن کاملRegulatory RNAs in Planarians.
The full scope of regulatory RNA evolution and function in epigenetic processes is still not well understood. The development of planarian flatworms to be used as a simple model organism for research has shown a great potential to address gaps in the knowledge in this field of study. The genomes of planarians encode a wide array of regulatory RNAs that function in gene regulation. Here, we revi...
متن کاملEngineering regulatory RNAs.
RNA has long been a favoured medium for in vitro evolution and engineering. Functional RNAs produced in vitro can bind small molecules (aptamers), possess catalytic activity (ribozymes) or do both (aptazymes). A plethora of recent work has shown similar strategies used naturally for gene regulation in bacteria. Interest in these natural systems has inspired an effort to engineer and evolve this...
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ژورنال
عنوان ژورنال: RNA Biology
سال: 2013
ISSN: 1547-6286,1555-8584
DOI: 10.4161/rna.27102